PRK2 Mouse Monoclonal Antibody
Product Specifications
Background
Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.
Product Name Alternative
PKN2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606
Gene Name
PRK2
Gene ID
5586
Swiss Prot
Q16513
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA, FC
Field of Research
Apoptosis, PI3K-Akt signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
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