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KI67 Mouse Monoclonal Antibody

Product Specifications

Background

Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase) . It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index) . In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Product Name Alternative

KIA; Ki-67; MKI67

Gene Name

KI67

Gene ID

4288

Swiss Prot

P46013

Host

Mouse

Reactivity

Human, Mouse, Rat, Rabbit, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA, FC

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

358kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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