NF-κB p65 Mouse Monoclonal Antibody
Product Specifications
Background
NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.
Product Name Alternative
NFkappaB p65; p65; NFKB3; RELA
Gene Name
NF-κB p65
Gene ID
5970
Swiss Prot
Q04206
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
PI3K-Akt signaling pathway, MAPK signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:500, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
65kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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