ISL1 Mouse Monoclonal Antibody
Product Specifications
Background
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Product Name Alternative
Isl-1; ISLET1
Gene Name
ISL1
Gene ID
3670
Swiss Prot
P61371
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
IHC, ICC, ELISA
Purification
Affinity Purification
Dilution
IHC 1:100-1:500, ICC 1:50-1:500, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide.
Modification
Unmodified
Molecular Weight
39kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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