CDK2 Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) . Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
Product Name Alternative
P33
Gene Name
CDK2
Gene ID
1017
Swiss Prot
P24941
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC, ELISA, FC
Field of Research
PI3K-Akt signaling pathway, mTOR signaling pathway
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide
Modification
Unmodified
Molecular Weight
33.9kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Curated Selection
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