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MAPK3 Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Product Name Alternative

ERK1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; MGC20180

Gene Name

MAPK3

Gene ID

5595

Swiss Prot

P27361

Host

Mouse

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC, ELISA, FC

Field of Research

Apoptosis, TGF-beta signaling pathway, PI3K-Akt signaling pathway, mTOR signaling pathway, MAPK signaling pathway, Jak-STAT signaling pathway

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Modification

Unmodified

Molecular Weight

44kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Frequently Asked Questions

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