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PRKAA1 Mouse Monoclonal Antibody

Product Specifications

Background

The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK) . AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Product Name Alternative

AMPK; AMPKa1; MGC33776; MGC57364; PRKAA1

Gene Name

PRKAA1

Gene ID

5562

Swiss Prot

Q13131

Host

Mouse

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC, ELISA, FC

Field of Research

Autophagy, Wnt signaling pathway, PI3K-Akt signaling pathway

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ICC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide.

Modification

Unmodified

Molecular Weight

64kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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