KI67 Mouse Monoclonal Antibody
Product Specifications
Background
Ki67, also known as MKI67, it is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase) . It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index) . In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Product Name Alternative
KIA; Ki-67; MKI67
Gene Name
KI67
Gene ID
4288
Swiss Prot
P46013
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
IHC, ICC, ELISA
Purification
Affinity Purification
Dilution
IHC 1:100-1:500, ICC 1:50-1:500, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.
Modification
Unmodified
Molecular Weight
358kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG2b
Available Sizes
Curated Selection
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