XRCC1 Mouse Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Product Name Alternative
RCC; SCAR26
Gene Name
XRCC1
Gene ID
7515
Swiss Prot
P18887
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA, FC
Purification
Affinity Purification
Dilution
WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400
Form
Liquid
Buffer
Purified antibody in PBS with 0.05% sodium azide
Modification
Unmodified
Molecular Weight
69.5kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Isotype
Mouse IgG1
Available Sizes
Frequently Asked Questions
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