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XRCC1 Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Product Name Alternative

RCC; SCAR26

Gene Name

XRCC1

Gene ID

7515

Swiss Prot

P18887

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA, FC

Purification

Affinity Purification

Dilution

WB 1:500-1:2000, IHC 1:200-1:1000, ELISA 1:5000-1:20000, FC 1:200-1:400

Form

Liquid

Buffer

Purified antibody in PBS with 0.05% sodium azide

Modification

Unmodified

Molecular Weight

69.5kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Isotype

Mouse IgG1

Available Sizes

Curated Selection

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