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Pyruvate Dehydrogenase E1 alpha (3H2) Mouse Monoclonal Antibody

Product Specifications

Background

The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) . Catalyzes the removal of CO2 from pyruvate. Mutations in the α subunits of pyruvate dehydrogenase (E1) lead to congenital defects that are usually associated with lactic acidosis, neurodegeneration and early death.

Product Name Alternative

Mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate dehydrogenase E1 component subunit alpha; somatic form; mitochondrial; somatic form.

Gene Name

PDHA1

Gene ID

5160

Swiss Prot

P08559

Host

Mouse

Reactivity

Human, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF

Field of Research

Signal Transduction

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Molecular Weight

Calculated MW: 43 kDa; Observed MW: 43 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/AMM03428_Enkilife_EN.pdf

Isotype

IgG1

Available Sizes

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