P53 (2D10) Mouse Monoclonal Antibody
Product Specifications
Background
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
Product Name Alternative
TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Gene Name
TP53
Gene ID
7157
Swiss Prot
P04637
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Unmodified
Molecular Weight
Calculated MW: 44 kDa; Observed MW: 53 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG1
Available Sizes
Curated Selection
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