CD45 (8C1) Mouse Monoclonal Antibody
Product Specifications
Background
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Product Name Alternative
GP180; L CA; CD45 antigen
Gene Name
Ptprc
Gene ID
19264
Swiss Prot
P06800
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Field of Research
Immunology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Unmodified
Molecular Weight
Calculated MW: 145 kDa; Observed MW: 145 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6333212-01 0.2 mL
PHACTR3, NT (PHACTR3, C20orf101, SCAPIN1, Phosphatase and actin regulator 3, Scaffold-associated PP1-inhibiting protein) (APC)
Ask
View Details MBS6333212-02 5x 0.2 mL
PHACTR3, NT (PHACTR3, C20orf101, SCAPIN1, Phosphatase and actin regulator 3, Scaffold-associated PP1-inhibiting protein) (APC)
Ask
View Details