ATP Citrate Lyase (3D9) Mouse Monoclonal Antibody
Product Specifications
Background
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
Product Name Alternative
ACLY; ATP-citrate synthase; ATP-citrate; pro-S-) -lyase; ACL; Citrate cleavage enzyme
Gene Name
ACLY
Gene ID
47
Swiss Prot
P53396
Host
Mouse
Reactivity
Human, Mouse, Monkey
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Field of Research
Signal Transduction
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200, FC 1:50-1:100
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Unmodified
Molecular Weight
Calculated MW: 121 kDa; Observed MW: 121 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG2a
Available Sizes
Curated Selection
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