Phospho-ERK1/2 (Tyr222/Tyr205) (10C8) Mouse Monoclonal Antibody
Product Specifications
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Product Name Alternative
MAPK1/MAPK3
Gene Name
MAPK1/MAPK3
Gene ID
5595/5594
Swiss Prot
P27361/P28482
Host
Mouse
Reactivity
Human, Rat, Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
IHC 1:50-1:100
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG1
Available Sizes
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