MonoMethyl-p53 (Lys370) (4C7) Mouse Monoclonal Antibody

Product Specifications

Background

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Product Name Alternative

Cellular tumor antigen p53; Cys 51 stop; Tp53; Tumor protein p53

Gene Name

TP53

Gene ID

7157

Swiss Prot

P04637

Host

Mouse

Reactivity

Human, Rat, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology

Purification

Affinity Purification

Dilution

IHC 1:50-1:100

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Methylated

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

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