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MLH1 (4C1) Mouse Monoclonal Antibody

Product Specifications

Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.

Product Name Alternative

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Gene Name

MLH1

Gene ID

4292

Swiss Prot

P40692

Host

Mouse

Reactivity

Human, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Ascitic Fluid

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200

Form

Liquid

Buffer

Ascitic fluid containing 0.03% sodium azide.

Modification

Unmodified

Molecular Weight

Calculated MW: 85 kDa; Observed MW: 85 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

Curated Selection

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