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KDM1A (1B2) Mouse Monoclonal Antibody

Product Specifications

Background

Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

Product Name Alternative

KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

Gene Name

KDM1A

Gene ID

23028

Swiss Prot

O60341

Host

Mouse

Reactivity

Human, Mouse, Monkey

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Epigenetics and Nuclear Signaling

Purification

Ascitic Fluid

Dilution

WB 1:500-1:1000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Molecular Weight

Calculated MW: 93 kDa; Observed MW: 93 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

Frequently Asked Questions

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