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ERK1 (8G6) Mouse Monoclonal Antibody

Product Specifications

Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Product Name Alternative

MAPK3

Gene Name

MAPK3

Gene ID

5595

Swiss Prot

P27361

Host

Mouse

Reactivity

Human, Rat, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cell Biology

Purification

Affinity Purification

Dilution

IHC 1:50-1:100

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

Frequently Asked Questions

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