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CD4 (7H9) Mouse Monoclonal Antibody

Product Specifications

Background

Cluster of Differentiation 4 (CD4) is a glycoprotein composed of an amino-terminal extracellular domain (four domains: D1-D4 with Ig-like structures), a transmembrane part and a short cytoplasmic tail. CD4 is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells, and plays an important role in the development and activation of T cells. On T cells, CD4 is the co-receptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen–Major Histocompatibility Complex (MHC) .

Product Name Alternative

CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4

Gene Name

CD4

Gene ID

920

Swiss Prot

P01730

Host

Mouse

Reactivity

Human, Rat, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Immunology

Purification

Affinity Purification

Dilution

IHC 1:50-1:100

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

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