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CD133 (8F2) Mouse Monoclonal Antibody

Product Specifications

Background

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Name Alternative

Prominin-1; Antigen AC133; Prominin-like protein 1; CD133.

Gene Name

PROM1

Gene ID

8842

Swiss Prot

O43490

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience

Purification

Affinity Purification

Dilution

WB 1:500-1:1000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Molecular Weight

Calculated MW: 97 kDa; Observed MW: 133 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG2b

Available Sizes

Curated Selection

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