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ATM (9F7) Mouse Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.

Product Name Alternative

ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated

Gene Name

ATM

Gene ID

472

Swiss Prot

Q13315

Host

Mouse

Reactivity

Human, Rat, Mouse

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Purification

Dilution

IHC 1:50-1:100

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG1

Available Sizes

Curated Selection

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