Claudin-2 Mouse Monoclonal Antibody (8H11)
Product Specifications
Background
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010], function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity., similarity:Belongs to the claudin family., subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
Product Name Alternative
Claudin-2 (SP82)
Gene Name
CLDN2 PSEC0059 SP82 UNQ705/PRO1356
Gene ID
9075
Swiss Prot
P57739
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:500, ICC/IF 1:100-1:500
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
25kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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