HSP90 α (1F6) Mouse Monoclonal Antibody

The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence., function:Molecular chaperone., function:Molecular chaperone. Has ATPase activity., similarity:Belongs to the heat shock protein 90 family., subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV., subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1.