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CDX2 (14H6) Mouse Monoclonal Antibody

Product Specifications

Background

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012], function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine., PTM:Phosphorylation of Ser-60 mediates the transactivation capacity., similarity:Belongs to the Caudal homeobox family., similarity:Contains 1 homeobox DNA-binding domain.

Product Name Alternative

CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2

Gene Name

CDX2

Gene ID

1045

Swiss Prot

Q99626

Host

Mouse

Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:200, ICC/IF 1:100-1:200

Form

Liquid

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

Modification

Unmodified

Molecular Weight

42kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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