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Wnt5a Rabbit Polyclonal Antibody

Product Specifications

Background

Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.

Product Name Alternative

WNT5A; Protein Wnt-5a

Gene Name

WNT5A

Gene ID

7474

Swiss Prot

P41221

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC

Field of Research

Neuroscience

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, FC 1:50-1:100

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 42 kDa; Observed MW: 42 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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