Ubiquitin Conjugating Enzyme E2 A/B Rabbit Polyclonal Antibody
Product Specifications
Background
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.
Product Name Alternative
UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B
Gene Name
UBE2A/UBE2B
Gene ID
7319/7320
Swiss Prot
P49459/P63146
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Unmodified
Molecular Weight
Calculated MW: 17 kDa; Observed MW: 17 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Septin 3 (SEPT3) Mouse Monoclonal Antibody [Clone ID: LBI3F4]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
abx412659 100 µg
Receptor-Type Tyrosine-Protein Phosphatase C / CD45 (PTPRC) Antibody (FITC)
Ask
View Details 
F1170-01 5 g
(S) -2- ((((9H-Fluoren-9-yl) Methoxy) Carbonyl) Amino) -4-Oxo-4- (Tritylamino) Butanoicacid
Ask
View Details F1170-02 25 g
(S) -2- ((((9H-Fluoren-9-yl) Methoxy) Carbonyl) Amino) -4-Oxo-4- (Tritylamino) Butanoicacid
Ask
View Details