Menin Rabbit Polyclonal Antibody

Product Specifications

Background

Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL) -containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

Product Name Alternative

MEN1; SCG2; Menin

Gene Name

MEN1

Gene ID

4221

Swiss Prot

O00255

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, IP

Field of Research

Epigenetics and Nuclear Signaling

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 68 kDa; Observed MW: 68 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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