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Insulin Degrading Enzyme Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.

Product Name Alternative

INSULYSIN; Insulin degrading enzyme; IDE

Gene Name

IDE

Gene ID

3416

Swiss Prot

P14735

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC

Field of Research

Neuroscience

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, IHC 1:50-1:100

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 118 kDa; Observed MW: 118 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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