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HLA DQB1/2 Rabbit Polyclonal Antibody

Product Specifications

Background

Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases.

Product Name Alternative

HLA-DQB1; HLA-DQB; HLA class II histocompatibility antigen; DQ beta 1 chain; MHC class II antigen DQB1; HLA-DQB2; HLA-DXB; HLA class II histocompatibility antigen; DQ beta 2 chainHLA class II histocompatibility antigen; DX beta chain; MHC class II antigen DQB2

Gene Name

HLA-DQB1/HLA-DQB2

Gene ID

3119/3120

Swiss Prot

P01920/P05538

Host

Rabbit

Reactivity

Human

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ELISA

Field of Research

Immunology

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Molecular Weight

Calculated MW: 30 kDa; Observed MW: 30 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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