Growth Hormone Receptor Rabbit Polyclonal Antibody

Product Specifications

Background

Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Product Name Alternative

GHR; Growth hormone receptor; GH receptor; Somatotropin receptor

Gene Name

GHR

Gene ID

2690

Swiss Prot

P10912

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, FC

Field of Research

Signal Transduction

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, FC 1:50-1:100

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 72 kDa; Observed MW: 140 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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