FADD Rabbit Polyclonal Antibody
Product Specifications
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Product Name Alternative
FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
Gene Name
Fadd
Gene ID
14082
Swiss Prot
Q61160
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, FC
Field of Research
Cell Biology
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, FC 1:50-1:100
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 23 kDa; Observed MW: 28 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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