DGCR8 Rabbit Polyclonal Antibody
Product Specifications
Background
Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.
Product Name Alternative
DGCR8; DGCRK6; Gy1; C22orf12; D16Wis2; pasha
Gene Name
DGCR8
Gene ID
54487
Swiss Prot
Q8WYQ5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, IP
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200, IP 1:20-1:50
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 86 kDa; Observed MW: 100 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-9233R-BF488 100 µL
RNF180 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Sign In for Pricing
View Details 
AQB89483-01 50 mg
3,3-Dimethyl-5-oxo-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester-d3
Sign In for Pricing
View Details AQB89483-02 0.5 g
3,3-Dimethyl-5-oxo-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester-d3
Sign In for Pricing
View Details 126263-TRI 200 pieces per CAR
Cryo.s, U, skirt, 2ml, polypropylene, graduation, writing area, neutral screw cap, external thread, subpacked per 10 pieces, triple packed, STERILE, SAL 10−6, 200 pieces per CAR
Sign In for Pricing
View Details bs-3370R-FITC 100 µL
Phospho-Rad17 (Ser645) Polyclonal Antibody, FITC Conjugated
Sign In for Pricing
View Details