CD130 Rabbit Polyclonal Antibody
Product Specifications
Background
The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.
Product Name Alternative
Interleukin-6 receptor subunit beta , IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, CDw130
Gene Name
IL6ST
Gene ID
3572
Swiss Prot
P40189
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
Cell Biology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Modification
Unmodified
Molecular Weight
Calculated MW: 104 kDa; Observed MW: 130-140kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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