Axin 2 Rabbit Polyclonal Antibody

Product Specifications

Background

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

Product Name Alternative

Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin

Gene Name

AXIN2

Gene ID

8313

Swiss Prot

Q9Y2T1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Field of Research

Cell Biology

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Unmodified

Molecular Weight

Calculated MW: 94 kDa; Observed MW: 94 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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