Axin 2 Rabbit Polyclonal Antibody
Product Specifications
Background
Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.
Product Name Alternative
Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin
Gene Name
AXIN2
Gene ID
8313
Swiss Prot
Q9Y2T1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF
Field of Research
Cell Biology
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 94 kDa; Observed MW: 94 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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