Phospho-YAP (Ser127) Rabbit Polyclonal Antibody

Product Specifications

Background

YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Product Name Alternative

YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Gene Name

YAP1

Gene ID

10413

Swiss Prot

P46937

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Field of Research

Signal Transduction

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:100-1:200

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Phosphorylated

Molecular Weight

Calculated MW: 54 kDa; Observed MW: 65 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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