Phospho-Smad3 (Ser425) Rabbit Polyclonal Antibody
Product Specifications
Background
Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad) . Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.
Product Name Alternative
SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
Gene Name
SMAD3
Gene ID
4088
Swiss Prot
P84022
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Signal Transduction
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 48 kDa; Observed MW: 58 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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