Phospho-Rb (Ser807) Rabbit Polyclonal Antibody

Product Specifications

Background

Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.

Product Name Alternative

RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Gene Name

RB1

Gene ID

5925

Swiss Prot

P06400

Host

Rabbit

Reactivity

Human, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF

Field of Research

Cell Biology

Purification

Affinity Purification

Dilution

WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200

Form

Liquid

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Modification

Phosphorylated

Molecular Weight

Calculated MW: 106 kDa; Observed MW: 110 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GR187082 96 Well

Nori® Turkey CARD11/CARMA1 ELISA Kit

Ask

View Details

NBP3-20997CL1 0.1 mL

Rabbit Monoclonal STAT6 Antibody (STAT6/7774R) [CoraFluor 1]

Ask

View Details

MBS6474245-01 0.1 mL

Ephrin A4 (EFNA4) (AP)

Ask

View Details

MBS6474245-02 5x 0.1 mL

Ephrin A4 (EFNA4) (AP)

Ask

View Details

NBP2-98461AF532 0.1 mL

Rabbit Polyclonal FDPS Antibody [Alexa Fluor 532]

Ask

View Details