Phospho-mTOR (Ser2448) Rabbit Polyclonal Antibody
Product Specifications
Background
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Product Name Alternative
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
Gene Name
MTOR
Gene ID
2475
Swiss Prot
P42345
Host
Rabbit
Reactivity
Human, Mouse, Pig
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
Cell Biology
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 289 kDa; Observed MW: 289 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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