Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody
Product Specifications
Background
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .
Product Name Alternative
IRS1; Insulin receptor substrate 1; IRS-1
Gene Name
IRS1
Gene ID
3667
Swiss Prot
P35568
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Tags & Cell Markers
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 132 kDa; Observed MW: 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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