Phospho-IRE1 (Ser724) Rabbit Polyclonal Antibody
Product Specifications
Background
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Product Name Alternative
ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
Gene Name
ERN1
Gene ID
2081
Swiss Prot
O75460
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 110 kDa; Observed MW: 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
251904-ML490 100 µL
SNAPC4 (Small Nuclear RNA Activating Complex, Polypeptide 4, 190kD, FLJ13451, PTFalpha, SNAP190) (MaxLight 490)
Ask
View Details 