Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Rabbit Polyclonal Antibody
Product Specifications
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Product Name Alternative
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Gene Name
IGF1R
Gene ID
3480
Swiss Prot
P08069
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Signal Transduction
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 155 kDa; Observed MW: 155 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
302417-ML750 100 µL
Epcam (Epithelial Cell Adhesion Molecule, Ep-CAM, Epithelial GlycoProtein 314, EGP314, mEGP314, Protein 289A, Tumor-Associated Calcium signal Transducer 1, CD326, Epcam, Tacstd1) (MaxLight 750) discontinued
Ask
View Details 
