Phospho-eIF4E (Ser209) Rabbit Polyclonal Antibody
Product Specifications
Background
EIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Product Name Alternative
EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Gene Name
EIF4E
Gene ID
1977
Swiss Prot
P06730
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, IP
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, IHC 1:50-1:100, ICC/IF 1:50-1:200, IP 1:20-1:50
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 25 kDa; Observed MW: 25 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1013990-01 0.02 mg (E-Coli)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details MBS1013990-02 0.1 mg (E-Coli)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details 
MBS1013990-03 0.02 mg (Yeast)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details MBS1013990-04 0.1 mg (Yeast)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details 
MBS1013990-05 0.02 mg (Baculovirus)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details MBS1013990-06 0.02 mg (Mammalian-Cell)
Recombinant Tetrahymena pyriformis Histone H2A.1 (HTA2)
Ask
View Details