Phospho-4E BP1 (Thr37) Rabbit Polyclonal Antibody
Product Specifications
Background
Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.
Product Name Alternative
EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I
Gene Name
EIF4EBP1
Gene ID
1978
Swiss Prot
Q13541
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Purification
Dilution
WB 1:500-1:1000, IHC 1:50-1:100
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 13 kDa; Observed MW: 18 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
SC402920 10 µg
MIR7037 Mouse MicroRNA Expression Plasmid (MI0022886)
Sign In for Pricing
View Details 
K6655702 1.0 µg DNA
Reg3g sgRNA CRISPR Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details MBS6011006-01 0.1 mg
Fkbp8 (Peptidyl-prolyl Cis-trans Isomerase FKBP8, PPIase FKBP8, 38kD FK506-binding Protein, 38kD FKBP, FKBP-38, mFKBP38, FK506-binding Protein 8, FKBP-8, FKBPR38, Rotamase, Fkbp38, Sam11)
Sign In for Pricing
View Details MBS6011006-02 5x 0.1 mg
Fkbp8 (Peptidyl-prolyl Cis-trans Isomerase FKBP8, PPIase FKBP8, 38kD FK506-binding Protein, 38kD FKBP, FKBP-38, mFKBP38, FK506-binding Protein 8, FKBP-8, FKBPR38, Rotamase, Fkbp38, Sam11)
Sign In for Pricing
View Details MBS520106-01 0.1 mg
Anti-Mouse CD4 Biotin (Clone YTS 191.1) (rat IgG2b)
Sign In for Pricing
View Details