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Acetyl-p53 (Lys370) Rabbit Polyclonal Antibody

Product Specifications

Background

Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Product Name Alternative

Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53

Gene Name

TP53

Gene ID

7157

Swiss Prot

P04637

Host

Rabbit

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ICC/IF, IP

Field of Research

Cell Biology

Purification

Affinity Chromatography

Dilution

WB 1:500-1:1000, ICC/IF 1:50-1:200, IP 1:20-1:50

Form

Liquid

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Acetylated

Molecular Weight

Calculated MW: 44 kDa; Observed MW: 53 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/APRab01331_Enkilife_EN.pdf

Isotype

IgG

Available Sizes

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