Nop132 Rabbit Polyclonal Antibody

NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth (Sekiguchi et al., 2004 [PubMed 14660641]) .[supplied by OMIM, Mar 2008], function:Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells., induction:Up-regulated in diffuse-type gastric cancers., PTM:Phosphorylated., similarity:Contains 1 RRM (RNA recognition motif) domain., subunit:Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7., tissue specificity:Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.