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DRS-1 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011], catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., function:Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species., similarity:Contains 1 ACB (acyl-CoA-binding) domain., similarity:In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., tissue specificity:Abundant in heart, skeletal muscle and liver.

Product Name Alternative

ECI2; DRS1; HCA88; PECI; Enoyl-CoA delta isomerase 2; mitochondrial; DRS-1; Delta (3), delta (2) -enoyl-CoA isomerase; D3, D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hep

Gene Name

ECI2

Gene ID

10455

Swiss Prot

O75521

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Field of Research

Fatty acid metabolism

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

40kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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