CPTI-M Rabbit Polyclonal Antibody

The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009], catalytic activity:ATP + choline = ADP + O-phosphocholine., catalytic activity:ATP + ethanolamine = ADP + O-phosphoethanolamine., catalytic activity:Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine., miscellaneous:This protein is produced by a bicistronic gene which also produces the CHKB protein from a non-overlapping reading frame., miscellaneous:This protein is produced by a bicistronic gene which also produces the CPT1B protein from a non-overlapping reading frame., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:Belongs to the carnitine/choline acetyltransferase family., similarity:Belongs to the choline/ethanolamine kinase family., tissue specificity:Strong expression in heart and skeletal muscle. No expression in liver and kidney.

CPT1B; KIAA1670; Carnitine O-palmitoyltransferase 1; muscle isoform; CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein