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PBFE Rabbit Polyclonal Antibody

Product Specifications

Background

Catalytic activity: (3S) -3-hydroxyacyl-CoA = trans-2 (or 3) -enoyl-CoA + H (2) O., catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., catalytic activity: (S) -3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH., disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family., similarity:In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., subunit:Monomer., tissue specificity:Liver and kidney. Lower amounts seen in the brain., catalytic activity: (3S) -3-hydroxyacyl-CoA = trans-2 (or 3) -enoyl-CoA + H (2) O., catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., catalytic activity: (S) -3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH., disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family., similarity:In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., subunit:Monomer., tissue specificity:Liver and kidney. Lower amounts seen in the brain.

Product Name Alternative

EHHADH; ECHD; Peroxisomal bifunctional enzyme; PBE; PBFE

Gene Name

EHHADH

Gene ID

1962

Swiss Prot

Q08426

Host

Rabbit

Reactivity

Human, Rat

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Field of Research

Fatty acid metabolism; Valine; leucine and isoleucine degradation; Lysine degradation; Tryptophan metabolism; beta-Alanine metabolism; Propanoate metabolism; Butanoate metabolism; Limonene and pinene degradation; PPAR

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

80kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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