PBFE Rabbit Polyclonal Antibody
Product Specifications
Background
Catalytic activity: (3S) -3-hydroxyacyl-CoA = trans-2 (or 3) -enoyl-CoA + H (2) O., catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., catalytic activity: (S) -3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH., disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family., similarity:In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., subunit:Monomer., tissue specificity:Liver and kidney. Lower amounts seen in the brain., catalytic activity: (3S) -3-hydroxyacyl-CoA = trans-2 (or 3) -enoyl-CoA + H (2) O., catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., catalytic activity: (S) -3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH., disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family., similarity:In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., subunit:Monomer., tissue specificity:Liver and kidney. Lower amounts seen in the brain.
Product Name Alternative
EHHADH; ECHD; Peroxisomal bifunctional enzyme; PBE; PBFE
Gene Name
EHHADH
Gene ID
1962
Swiss Prot
Q08426
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Fatty acid metabolism; Valine; leucine and isoleucine degradation; Lysine degradation; Tryptophan metabolism; beta-Alanine metabolism; Propanoate metabolism; Butanoate metabolism; Limonene and pinene degradation; PPAR
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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